How to Wash a Mouthguard: Safe Cleaning Guide & Pro Tips
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If you are wondering how to wash a mouthguard without warping the plastic or leaving a chemical taste, you need a routine based on science, not guesswork. A mouthguard sits against your gums for hours, creating a warm, humid environment perfect for bacteria. Cleaning it effectively requires more than a quick rinse under the tap.
Keep Your Smile Protector Pristine: Why Proper Mouthguard Care Matters
Whether you are an athlete, a parent of a child with braces, or managing bruxism (teeth grinding), your mouthguard is an essential shield. However, because it spends hours inside the oral cavity, it quickly becomes a host for biofilm.
This isn't just "dirt." Biofilm is a sticky, complex structure where saliva, food particles, and microbes like Streptococcus mutans (the bacteria behind cavities) and Candida albicans (fungus causing thrush) bond to the plastic. If you notice a slimy texture, a cloudy white film, or a stale "locker room" smell, colonies are already established. Proper cleaning breaks this biological glue, protecting both your oral health and the device's longevity.
TL;DR: The Quick & Easy Mouthguard Clean
To effectively clean a mouthguard, rinse it thoroughly with cool water immediately after use. Gently brush with a dedicated soft-bristled toothbrush and a mild, pH-neutral liquid soap. Store it completely dry in a ventilated case. Never use hot water or toothpaste.
The Science: Polymers and Pathogens
Understanding the materials prevents you from ruining the fit. Most mouthguards are crafted from Ethylene-vinyl acetate (EVA), a thermoplastic copolymer. Custom dental appliances may use Poly(methyl methacrylate) (PMMA).
- Thermal Degradation: These materials have specific glass transition temperatures. Exposing EVA to water above 40°C (104°F) causes the polymer chains to relax and contract. This ruins the custom fit you paid for.
- Chemical Sensitivity: Much like when you learn how to wash vinyl safely, understanding the polymer structure of your mouthguard prevents damage. Harsh alkalis (bleach) or alcohols strip the plasticizers from EVA, making the guard brittle and prone to cracking.

The FabricCare101 Cleaning Protocol
Follow this clinical routine to keep your appliance hygienic and clear.
Step 1: Immediate Hydro-Rinse
The second the guard leaves your mouth, rinse it under cool running water. Do not wait. Once saliva dries, the proteins harden and adhere to the polymer, making removal significantly harder.
Step 2: Mechanical Debridement (The Daily Wash)
Chemicals alone cannot penetrate thick biofilm; you need friction.
- Apply a pea-sized drop of mild liquid dish soap to a soft-bristled toothbrush.
- Note: Designate a specific brush for this. Do not use your regular toothbrush, which carries toothpaste residue (abrasive) and oral bacteria.
- Gently scrub every surface. Pay attention to the inner channel where your teeth sit-this is the primary collection point for plaque.
- Why Dish Soap? It contains surfactants that emulsify lipids (fats) and loosen protein bonds without abrasion.
Step 3: Chemical Disinfection (The Weekly Soak)
Once a week, or if odors persist, use a chemical agent to kill microscopic pathogens.
- The Solution: Dissolve a specialized mouthguard cleaning tablet in a cup of cool water, or use a 3% Hydrogen Peroxide solution.
- The Method: Soak for 10 to 15 minutes.
- Warning: Do not soak for hours or overnight unless the specific product label advises it. Prolonged exposure can soften the surface of EVA materials.
Step 4: Final Rinse and Inspection
Rinse aggressively under cool water to remove all traces of soap or cleaning solution. Residual chemicals can irritate gum tissue. Inspect the guard for debris.
Step 5: The "Bone Dry" Technique
Shake off excess water. Place the guard on a clean lint-free towel. It must be 100% dry before storage. Bacteria require moisture to multiply. If you put a damp guard in a case, you are creating an incubator for mold.
Step 6: Ventilated Storage
Store the device in a rigid case with air holes. Just as you would follow a delicate process for a wash wig guide to protect synthetic fibers from humidity and heat, treat your mouthguard's EVA surface with similar care regarding environment.

Mouthguard Cleaning Agents: Compatibility & Efficacy Matrix
Use this chart to select the right cleaner for your specific device material.
| Cleaning Agent | Concentration | Mechanism | Best For | Material Compatibility |
|---|---|---|---|---|
| Mild Dish Soap | 1-2 drops | Surfactant: Emulsifies oils and debris. | Daily Cleaning | Safe for EVA & Acrylic (PMMA) |
| Hydrogen Peroxide | 3% Solution | Oxidation: Disrupts microbial cell walls. | Disinfection | Safe for EVA; Use caution with Acrylic |
| Denture Tablets | Follow Label | Effervescent/Enzymatic: Bubbles dislodge debris; enzymes break down proteins. | Weekly Deep Clean | Check label (some turn EVA cloudy) |
| White Vinegar | 50/50 with water | Acidic: Dissolves mineral (calcium) deposits. | Removing Scale | Safe for most; Rinse thoroughly |
| Chlorine Bleach | Any | Oxidation: Strong chemical attack. | NEVER USE | Destroys EVA & Acrylic |
| Alcohol Mouthwash | >20% Alcohol | Desiccation: Dries out cells. | AVOID | dries out plasticizers; causes cracking |
Expert Insights: Pro Tips for Longevity
- Mind the Water Hardness: If you live in an area with hard water, you may see white, chalky deposits on your guard. This is calcium carbonate scale. Use distilled or demineralized water for your weekly soaks to prevent this buildup.
- Ultrasonic Cleaning: For the deepest clean, use an ultrasonic cleaner. These devices use sound waves to create cavitation bubbles that implode against the surface, blasting away debris from microscopic crevices that brushes miss.
- The Toothpaste Ban: Never brush your guard with toothpaste. Toothpaste contains silica or baking soda designed to polish enamel (the hardest substance in the body). Plastic is soft. Toothpaste creates thousands of micro-scratches where bacteria hide. Avoid harsh scouring. Unlike when you wash a pizza stone safe cleaning where abrasion is sometimes necessary, scratching a mouthguard creates bacterial havens.
Common Mistakes to Avoid
- Boiling to "Sterilize": Stop. Unless you are molding a new "boil-and-bite" guard, boiling water will warp your device instantly.
- Leaving it in the Gym Bag: A dark, damp gym bag is a fungus factory. Always remove the case and set it on a counter to air out when you get home.
- Sharing Guards: Never share a mouthguard. This transfers foreign bloodborne pathogens and oral flora that your immune system may not handle.
FAQ: Mouthguard Hygiene
Can I use regular mouthwash to clean my mouthguard?
Generally, no. Most mouthwashes contain alcohol or dyes. Alcohol dries out the plastic, leading to cracks, and dyes can stain the clear material. If you must, use a clear, alcohol-free mouthwash for a quick rinse only.
How often should I replace my mouthguard?
Replace your guard every 6 to 12 months, or sooner if you notice fraying, holes, or if the fit becomes loose. A loose guard offers significantly reduced protection against impact.
Can I wash my mouthguard in the dishwasher?
No. The water temperature in a dishwasher typically exceeds 50°C (120°F), and the detergents are too abrasive. This will warp the mouthguard and degrade the plastic.
Does vinegar kill mold on a mouthguard?
Yes. A 30-minute soak in a solution of equal parts white vinegar and cool water is effective against many mold species and helps dissolve mineral buildup. Rinse thoroughly afterward to remove the sour taste.